San Francisco 49ers rookie running back Isaac Guerendo detailed his excitement to stay ready and learn when superstar ...

Isaac Guerendo is navigating his first NFL season, and though the San Francisco 49ers rookie running back has only logged 37 ...

Matthew Berry, Jay Croucher, and Connor Rogers highlight their top running back waiver wire adds Week 10, including Jaylen ...

There's no such thing as having too many running backs. Just ask the San Francisco 49ers. Jordan Mason, who is starting in ...

The good news is that with Mason, rookie Isaac Guerendo and some fancy footwork from Purdy, the 49ers are averaging 159.0 ...

San Francisco 49ers rookie running back Isaac Guerendo’s coachability and maturity has played a big role in his steady ...

San Francisco 49ers running back Isaac Guerendo was nominated for the Pepsi Zero Sugar Rookie of the Week Award after closing ...

San Francisco 49ers running back Isaac Guerendo has been nominated for the Pepsi Zero Sugar Rookie of the Week award after an ...

Watch all of San Francisco 49ers rookie running back Isaac Guerendo's best plays from his 102-yard game against the Dallas ...

Add as Handcuff ROSTERED IN: 16% of Leagues ANALYSIS: San Francisco 49ers running back Isaac Guerendo scored 19.2 PPR fantasy ...

Coach Kyle Shanahan told NBC sideline reporter Melissa Stark at halftime that the 49ers would open the second half with a ...

San Francisco 49ers rookie running back Isaac Guerendo took over for Jordan Mason (shoulder) and performed well in a 30-24 ...