The EMBO Journal7h
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal1d
Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication
YTHDF1 binds to m6A modification sites on SFTSV, decreasing the stability of SFTSV RNA and reducing translation efficiency of SFTSV proteins. SFTSV protein NSs promotes YTHDF1 lactylation to inhibit ...
The EMBO Journal1d
Rett syndrome: interferon-γ to the rescue?
Rett syndrome is a severe neurodevelopmental disorder in girls, underpinned by mutations in the X-linked gene MECP2. In their ...
The EMBO Journal4d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal5d
Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The first step of successful infection by any ...
The EMBO Journal5d
Single-nucleus RNA-seq dissection of choroid plexus tumor cell heterogeneity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The genomic, genetic and cellular events ...
The EMBO Journal5d
Local translatome sustains synaptic function in impaired Wallerian degeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. After injury, severed axons separated from ...
The EMBO Journal5d
Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Diabetic cardiomyopathy (DC) leads to heart ...